Dein erstes Forum » A boiler makes for one of the m

Frontier Pharma: Parkinsons Disease Market Trends D.J. Humphries Hoodie , Regulations And Competitive Landscape Business Articles | March 9, 2016

"The Report Frontier Pharma: Parkinsons Disease - Identifying and Commercializing First-in-Class Innovation provides information on pricing, market analysis, shares Budda Baker Hoodie , forecast, and company profiles for key industry participants. - "



Description


Parkinson’s Disease (PD) is the second most common neurodegenerative disease after Alzheimer’s disease, affecting around 7.4 million people worldwide. It is caused by the progressive loss of dopamine-producing neurons in the substantia nigra within the basal ganglia. The main motor symptoms are tremors, bradykinesia and rigidity Haason Reddick Hoodie , although symptoms vary between individuals. As the disease progresses to more advanced stages, increasing symptoms and complications develop, which can cause severe disability in patients.


The current market offers a number of anti-PD treatment options which provide symptomatic relief. Levodopa is currently the gold standard therapy, with other drug classes including dopamine agonists and Monoamine Oxidase B (MAO-B) inhibitors also used to treat early and advanced cases. With no current treatment showing effectiveness in delaying the course of the disease Chase Edmonds Hoodie , PD remains incurable. The high unmet need for a disease-modifying therapy is reflected in the pipeline, where a high proportion of early-stage first-in-class programs target the potential pathogenic mechanisms underlying neurodegeneration.


Scope


PD is a crowded market with many neuromodulatory drug classes available. However, a disease-modifying therapy with neuroprotective effects is yet to be developed.


What are the primary mechanisms that are thought to contribute to neuronal death?


What are the major barriers facing the development of investigational neuroprotective candidates?


Analysis reveals a high level of innovation and diversity in the pipeline, with 121 first-in-class programs acting on 57 unique molecular targets.


Neuromodulatory targets remain the dominant target family Mason Cole Hoodie , particularly in the late-stage pipeline.


What are the first-in-class families with a significant presence?


How well do they align with the underlying pathways governing neuronal death in PD?


Some of the first-in-class targets have a potentially stronger chance of being translated into novel treatments for PD.


What is the scientific rationale behind these targets? How do they perform in Preclinical studies?


What are the commonly used disease models and the parameters measuring neuroprotective effects in PD animal studies?


Deals involving first-in-class PD products are more likely to be made in earlier stages of development than non-first-in-class deals.


What is the dominant molecular target in the PD deals landscape?


What are the promising first-in-class products still available for future licensing?


Download Detail Report With Complete TOC at:

Reasons to buy


This report will allow you to -


Understand the current clinical and commercial landscape by considering the proposed pathogenic processes underlying PD neurodegeneration, diagnosis, prognosis, and the available treatment options and their usage in early and advanced PD.


Visualize the composition of the PD market to highlight the current unmet needs in order to gain a competitive understanding of the key opportunities.


Analyze the PD pipeline and stratify by stage of development Christian Kirk Hoodie , molecule type, and molecular target - the diversity of molecular targets in the pipeline is extremely encouraging due to the multifaceted nature of PD.


Assess the therapeutic potential of first-in-class targets using a proprietary matrix that assesses and ranks first-in-class products according to clinical potential.


Target the most promising and innovative PD products for early-stage investment by analyzing trends in licensing and co-development deals and accessing a curated list of first-in-class therapies potentially open to deal-making opportunities.


Browse More PressRelease:



Contact


Mr. Nachiket


90 Sate Street, Suite 700


Albany, NY 12207


Tel: +1-518-621-2074


Website:

E: sales@

A boiler makes for one of the most fundamental systems in a refinery or plant. Ensuring the continuous and efficient functioning of a plant is important. This article explores how a boiler functions and how it impacts other aspects of a plant.